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ციპზოლი / CIPZOL | მედიკამენტები | vidal.ge

შემადგენლობა
1 გ კრემი შეიცავს: კლოტრიმაზოლს _ 10 მგ.
დამხმარე ნივთიერებები: თეთრირბილიპარაფინი, ცეტოსტეარილისსპირტი, ცეტომაკროგოლი 1000, მსუბუქითხევადიპარაფინი, მეთილპარაბენი, პროპილპარაბენი, პროპილენგლიკოლი, ნატრიუმისდიჰიდროფოსფატისდიჰიდრატი, ნატრიუმისჰიდროფოსფატიუწყლო, გასუფთავებულიწყალი.
ფარმაკოლოგიური თვისებები
ციპზოლი წამოადგენს ფართო სპექტრის სოკოს საწინააღმდეგო საშუალებას, რომლის აქტიური ნივთიერებაა კლოტრიმაზოლი (იმიდაზოლის წარმოებული). მისი მოქმედების მექანიზმი განპირობებულია სოკოს უჯრედის მემბრანაში შემავალი ერგოსტერინის სინთეზის დათრგუნვით, რაც იწვევს მემბრანის სტრუქტურისა და თვისებების შეცვლას და უჯრედისლიზისს.
გააჩნიაფუნგოსტატურიდაფუნგიციდურიმოქმედება. აქტიურია დერმატოფიტების, ობის, საფუარასოკოების (Candida, Torulopsisglabrata, Rhodotorula)მიმართ. პრეპარატსგააჩნიაანტიმიკრობულიმოქმედებაგრამდადებითი (სტაფილოკოკები, სტრეპტოკოკები) დაგრამუარყოფითიბაქტერიების (Bacteroides, Gardnerellavaginalis)ასევე, Trichomonasvaginalis, Malassezia furfur (Pityriasisversicolor-ისგამომწვევი) დაCorynebacteriumminussimum-ის (ერითრაზმისგამომწვევი) მიმართ.
ფარმაკოკინეტიკა
კლოტრიმაზოლი ცუდად შეიწოვება კანიდან და ლორწოვანი გარსიდან და პრაქტიკულად არ გააჩნია სისტემური მოქმედება. ეპიდერმისის ღრმა შრეებში კონცენტრაცია მეტია, ვიდრე დერმაში და კანქვეშა ქსოვილში და აჭარბებს დერმატოფიტებისთვის მინიმალურ დამთრგუნველ კონცენტრაციას.
ჩვენებები
დერმატოფიტებით, ობის, საფუარა და სხვა სოკოებით გამოწვეული დერმატომიკოზები, ერითრაზმა, ტრიქოფიტია, მიკოზები, პარონიქია, ნაირფერიპიტირიაზი, ქატოსებრილიქენი, კანდიდოზურივულვიტიდაბალანიტი.
მიღების წესები და დოზები
ციპზოლი 1% კრემიდაიტანებადაშეიზილებაწინასწარდაბანილ, გამშრალებულკანისდაზიანებულუბანზედამისგარშემოთხელიფენისსახით 2-3-ჯერდღეში. მკურნალობისხანგრძლივობადგინდებაინდივიდუალურადდაავადებისსიმძიმის, პათოლოგიური ცვლილებების ლოკალიზაციის და თერაპიის ეფექტურობის მიხედვით. როგორც წესი, მკურნალობის პერიოდი შეადგენს არანაკლებ 4 კვირას. ტერფისდერმატომიკოზების მკურნალობა გრძელდება კლინიკური სიმპტომების გაქრობის შემდგომ არანაკლებ 2-3 კვირისგანმავლობში.
გვერდითი მოვლენები
იშვიათად შესაძლოა გამოვლინდეს ადგილობრივი რეაქციები: კანისქავილი, წვის და ჩხვლეტის შეგრძნება, ერითემა, დაბებრება, შეშუპება, კანის გაღიზიანება და აქერცვლ ააპლიკაციის ადგილას.
ალერგიული რეაქციები: ქავილი, ჭინჭრისციება. იმშემთხვევაში, თუ გამოვლინდა ისეთი გვერდითი მოვლენა, რომელიც არ არის აღნიშნული გამოყენების ინსტრუქციაში, პაციენტმა უნდა მიმართოს მკურნალ ექიმს.
უკუჩვენება
მომატებული მგრძნობელობა პრეპარატის რომელიმე კომპონენტის მიმართ.
ორსულობა და ლაქტაცია
კლინიკური და ექსპერიმენტული კვლევებით არ იქნა დადასტურებული პრეპარატის უარყოფითი მოქმედება ორსულობის და ძუძუთი კვების პერიოდში. მიუხედავად ამისა, პრეპარატის დანიშვნის მიზანშეწონილობა უნდა გადაწყდეს ინდივიდუალურად ექიმის მიერ. პრეპარატის გამოყენება უშუალოდ სარძევე ჯირკვალზე ლაქტაციის პერიოდში უკუნაჩვენებია.
განსაკუთრებული მითითებები
ციპზოლი არ გამოიყენება ოფთალმოლოგიურ პრაქტიკაში. საჭიროა მოვერიდოთ პრეპარატის თვალთან კონტაქტს. ალერგიული რეაქციების გამოვლენის შემთხვევაში საჭიროა მკურნალობის შეწყვეტა. 4 კვირის განმავლობაში მკურნალობის არა ეფექტურობის შემთხვევაში საჭიროა დიაგნოზის ვერიფიცირება.
ბავშვებში პრეპარატის ეფექტურობა და უსაფრთხოება არ არის დადგენილი.
პრეპარატის ზემოქმედება ავტოტრანსპორტისა და მექანიზმების მართვის უნარზე:
პრეპარატი არ მოქმედებს სატრანსპორტო საშუალებების მართვის უნარსა და ყურადღების კონცენტრაციაზე.
ჭარბი დოზირება
გარეგანი გამოყენებისას ჭარბი დოზირების შემთხვევები არ არის გამოვლენილი.
პრეპარატის პერორალურად მიღების გაუთვალისწინებელ შემთხვევაში შესაძლოა გამოვლინდეს შემდეგი სიმპტომები: ანორექსია, გულისრევა, ღებინება, მუცლის ტკივილი, ღვიძლის ფუნქციის დარღვევა; იშვიათად – ძილიანობა, ჰალუცინაციები, გახშირებული შარდვა, კანის ალერგიული რეაქციები.
ამ შემთხვევაში საჭიროა აქტივირებული ნახშირის მიღება და სიმპტომური თერაპიის ჩატარება.
სხვა წამლებთან ურთიერთქმედება
ერთდროულად გამოყენების შემთხვევაში ამფოტერიცინი B, ნისტატინი, ნატამიცინი აქვეითებენკლოტრიმაზოლის ეფექტურობას.
კლოტრიმაზოლი არღვევს ლატექსისკონტრაცეპტივების მთლიანობას.
შენახვის პირობები და ვადები
ინახება არაუმეტეს 25ºC ტემპერატურაზე, სინათლისაგან დაცულ და ბავშვებისათვის მიუწვდომელ ადგილას. დაუშვებელია გაყინვა.
ვიზუალური დათვალიერების შედეგად აღმოჩენილი რაიმე სახის დეფექტის შემთხვევაში პრეპარატის მიღება დაუშვებელია.
ვარგისობისვადა :
3 წელი. შეფუთვაზე აღნიშნული ვადის გასვლის შემდეგ პრეპარატის გამოყენება დაუშვებელია.
აფთიაქში გაცემის წესი
გაიცემა ურეცეპტოდ.

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