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იხილეთ აფთიაქების ჩამონათვალი

ფუნგოტერბინი / Fungoterbin
საერთაშორისო დასახელება: ტერბინაფინი
სამკურნალო ფორმა: გარეგანი გამოყენების საცხი
შემადგენლობა:100გრ კრემი შეიცავს ტერბინაფინის ჰიდროქლორიდი 1.00გრ
დამხმარე ნივთიერებები – ბეთილჰიდროქსიტოლუოლი (დიბუნოლი)0.10გრ, შარდოვანა (კაბამიდი) 
0.50გრ,მაკროგოლის ცეტოსტერატი (ეუმულგინ) 1.50გრ, ცეტოსტეარილის სპირტი, პოლოქსამერი,პროპილენგლიკოლი 23.00მგ, თხევადი პარაფინი (სამრდიცინო ვაზელინის ზეთი) 35.00გრ, ვაზელინი 7.00 გრ, გასუფთავებული წყალი 100 გრ
აღწერა თეთრი ან თითქმის თეთრი ფერის საცხი მსუბუქი სუნით
ფარმაკოთერაპიული ჯგუფი: სოკოს საწინააღმდეგო პრეპარატი
ათქ კოდი : D01AE15

ფარმაკოლოგიური მოქმედება: სოკოს საწინააღმდეგო ადგილობრივი გამოყენების პრეპარატი, წარმოადგენს ალილამინს, და გააჩნია სოკოს საწინააღმდეგო აქტივობის ფართო სპექტრი.
განსხვავდება გამოხატული ეპიდერმოფიტულობით. ტერბინაფინი მიზანმიმართულად მოქმედებს სოკოვანი უჯრედის ციტოპლაზმურ მემბრანაზე. ტერბინაფინი მოქმედებს სტეროლის მეტაბოლიზმის ადრეულ სტადიაში, სქვალენეპოქსიდაზური ციკლის დონეზე.ამ ფერმენტის დატრგუნვის ხარჯზე, ტერბინაფინი აბრკოლებს ერგოსტეროლის ფორმირებას, რომელიც არის სოკოს უჯრედული კედლის ძირიტადი კომპონენტი, ხელს უსლის მათ შემდგომ გამრავლებას.ფუნგიციდური ეფექტი განპირობებულია  სქვალენის სოკოვან უჯრედში დაგროვებით,რომლებიც ახდენენ მემბრანიდან ლიპიდური კომპონენტების გამოდევნას. უჯრედის შიგნით დაგროვილი ლიპიდები, თანდატან იზრდებიან მოცულობაში,არღვევენ ციტოპლაზმურ მემბრანებს ,იწვევენ სოკოვანი უჯრედის განადგურებას.ფუნგოტერბინი აქტიურია ყველა დერმატოფიტების მიმართ.ტერბინაფინი ასევე ახდენს ანთებისსაწინაარმდეგო, ქავილის საწინააღმდეგო,კერატოზულ მოქმედებას,საცხის შემადგენლობაში შარდოვანას არსებობის ხარჯზე პრეპარატს გააჩნია დამარბილებელი ეფექტი, ხელს უწყობს ტერბინაფინის კანსი ღრმად შეღწევას.

ჩვენებები: კანის სოკოვანი დაავადებები, რომლებიც გამოწვეულია მგრძნობიარე მიკრობებით (ტრიქოფიტია მიკროსპორია,ეპიდერმოფიტია,რუბროფიტიაკანის კანდიდოზი)ტერფის მიკოზი/ტერფის სოკო-ტინეა პედის.ტანის მიკოზი ტინეა კორპორის.გლუვი კანის მიკოზის და მსხვილი ნაკეცების მიკოზის ჩათვლით.საზარდულის ეპიდერმოფიტია-ტინეა ცრარის.კანის ზედაპირული კანდიდოზი, გამოწვეული კანდიდას სახის სოკოებით-ჩანდიდა ალბიკანს,მრავალფეროვანი სირსველი(პიტყრიასის ვერსიკოლორ)

უკუჩვენებები: ჰიპერმგრძნობელობა ტერბინაფინის ან სხვა კომპონენტების მიმართ.
გამოიყენება სიფრთხილით; თირკმლის ან ღვიძლის გამოხატული უკმარისობა,ქრონიკული ალკოჰოლიზმი,ძვლის ტვინის სისხლის წარმოქმნის დათრგუნვა, სიმსივნე,ნივთიერებათა ცვლის
დარღვევა კიდურების სისხლძარღვების ოკლუზიური დაავადება,ორსულობა ლაქტაციის პერიოდი, ბავშვის ასაკი 2 წლამდე.(საკმარისი გამოცდილების არ არსებობის გამო)

გამოყენება ორსულობის და ლაქტაციის პერიოდში: შესაძლებელია დედისთვის მოსალოდნელი სარგებლის და ნაყოფის მიმართ პოტენციური რისკის მკაცრი შეფასების სემდეგ. ლაქტაციის დროს ფუნგოტერბინის საცხის გამოყენების აუცილებლობის შემთხვევაში, უნდა მოარიდოთ ჩვილი ფუნგოტერბინით დამუშავებულ ადგილთან კონტაქტს. არ არის რეკომენდირებული ფართო ზედაპიზე გამოყენება.

გამოყენების წესი და დოზირება: გარეგანი გამოყენების წინ აუცილებელი დაზიანებული ადგილის გასუფთავება და გაშრობა.ფუნგოტერბინი წაისმევა 1 ან 2 ჯერ დღეში დაზიანებულ კანზე და მიმდებარე ადგილას.წაისვით კრემის თხელი ფენა და ოდნავ შეიზილეთ კანზე.კანის ნაკეცებზე წასმისას (საზარდულივილის ადგილი დუნდულა სარძევე ჯირკვლის ქვეშ)რეკომენდებულია დოლბანდის საფენის დადება ტანის მსხვილ ნაკეცების ტერფების წვივის დერმატომიკოზი: დღეში 1ჯერ მკურნალობის ხანგრძლივობა 1 კვირა.ტერფის დერმატომიკოზი 1ჯერ დღეში მკურნალობის ხნგრძლივობა 1 კვირა.კანის კანდიდოზი 1-2 ჯერ დღეში მკურნალობის ხანგრძლივობა 1-2 კვირა.მრავალფეროვანი სირსველი 1-2 ჯერ დღეში მკურნალობის ხანგრძლივობა 1 კვირა.
 
გვერდითი ეფექტი: ადგილობრივი რეაქციები;ქავილი და კანის წვა ჰიპერემია (სიწითლე)წასმის ადგილას.არ არის საჭირო მკურნალობის შეწყვეტა
ალერგიული რეაქციები:გენერალიზირებული გამონაყარი, ჭინჭრის ცხელება, ანგიონევროზული შეშუპება.უნდა შეწყდეს მკურნალობა და მიმართოთ ექიმს.

ურთიერთქმედება სხვა სამკურნალო პრეპარატებტან: ფუნგოტერბინის საცხის ზემოქმედება სხვა სამკურნალო საშუალებებთან არ არის ცნობილი

გამოშვების ფორმა: გარეგანი გამოყენების საცხი 1%
15 გრ ალუმინის ან პოლიეთილენის ლამინატის ტუბი. ტუბი მოტავსებულია მუყაოს კოლოფში.
აფთიაქიდან გაცემის  წესი. გამოიყენება ექიმის დანიშნულების გარეშე.
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